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Complex Regional Pain Syndrome, or CRPS, is a chronic pain condition that often develops after an injury, surgery, or even minor trauma. While it is not very common, it can cause severe and long-lasting pain that feels out of proportion to the original issue. Understanding what CRPS is, how it affects the body, and what treatments are available can help patients get the right care early and improve their long-term outlook. What Is CRPS? While the exact cause is not fully understood, CRPS is believed to involve a combination of nerve dysfunction, inflammation, and abnormal pain signaling. Early diagnosis and treatment are essential in preventing it from progressing. Common Symptoms Symptoms may come and go or gradually worsen over time, which is why early evaluation is important. How CRPS Is Diagnosed Treatment Options for CRPS Physical and Occupational Therapy Medications Some patients may also benefit from short-term oral steroids or topical treatments to reduce sensitivity. Interventional Pain Treatments These treatments are designed to help interrupt the abnormal pain cycle and support long-term improvement. Psychological Support and Mind-Body Therapies When to Seek Medical Care Living With CRPS
CRPS is a condition where the nervous system reacts abnormally after an injury. The pain may start in an arm, leg, hand, or foot and may feel burning, throbbing, or intensely sensitive to touch. Swelling, temperature changes, skin color changes, and stiffness are also common. There are two types of CRPS.
Type 1 develops without confirmed nerve damage.
Type 2 occurs when there is known nerve injury.
Although symptoms vary, patients often notice:
• Persistent pain that feels stronger than expected for the injury
• Burning or stinging sensations
• Swelling and stiffness in the affected area
• Temperature changes including warmth or coolness
• Changes in skin color or texture
• Reduced movement or weakness
• Heightened sensitivity that makes even light contact painful
CRPS is diagnosed based on symptoms, medical history, and clinical exam. There is no single test that confirms it, but imaging and nerve studies may help rule out other conditions. Because early treatment can prevent long-term complications, seeing a pain specialist promptly can make a meaningful difference.
Treatment focuses on reducing pain, improving function, and preventing long-term disability. A combination of therapies often gives the best results.
Movement therapy is one of the most important parts of CRPS care. Gentle exercises help improve circulation, restore mobility, and retrain the nervous system. Occupational therapy helps patients adapt daily activities and protect the affected limb.
Several medications may help manage symptoms, including:
• Anti-inflammatory drugs
• Neuropathic pain medications
• Muscle relaxants
• Medications that support nerve healing
For patients who need additional relief, pain specialists may recommend:
• Sympathetic nerve blocks to reduce overactive pain signals
• Ketamine infusions for severe or persistent cases
• Spinal cord stimulation to calm nerve activity
• Intravenous therapies that target inflammation or nerve dysfunction
Chronic pain affects both the body and mind. Cognitive behavioral therapy, relaxation training, and mindfulness can help patients manage stress, reduce pain intensity, and cope with the emotional impact of the condition.
If you notice persistent pain, swelling, or unusual sensitivity after an injury, it is important to see a doctor as soon as possible. Early treatment offers the best chance of reducing symptoms and preventing more advanced stages of CRPS.
Although CRPS can be challenging, many patients improve with a comprehensive treatment plan. Working closely with a pain specialist, staying consistent with therapy, and addressing symptoms early can lead to better long-term outcomes and improved function.
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